New source of fat tissue stem cells discovered
Researchers have found a new source of stem cells that produce fat tissue, findings presented today at the European Congress of Endocrinology in Wrocław, Poland, show. This unique in vitro human stem...
View ArticleGenomic 'dark matter' of embryonic lungs controls proper development of airways
It's a long way from DNA to RNA to protein, and only about two percent of a person's genome is eventually converted into proteins. In contrast, a much higher percentage of the genome is transcribed...
View ArticleLong-lived breast stem cells could retain cancer legacy
Researchers from Melbourne's Walter and Eliza Hall Institute have discovered that breast stem cells and their 'daughters' have a much longer lifespan than previously thought, and are active in puberty...
View ArticleProtein seipin regulates fat development through cytoskeleton remodeling
People with mutations in a gene called BSCL2 suffer from a rare medical condition known as lipodystrophy in which fat tissue is lost from where it is supposed to accumulate while being deposited at...
View ArticleStudy identifies gene important to breast development and breast cancer
A new study in Cell Reports identifies a gene important to breast development and breast cancer, providing a potential new target for drug therapies to treat aggressive types of breast cancer.
View ArticleIntelligent prosthetic liners could ease pain for lower limb amputees
A new device could help to relieve the pain and discomfort experienced by thousands of amputees as a result of poorly fitting replacement lower limbs. Researchers have been awarded Biomedical Catalyst...
View ArticleNew technique uses 'simulated' human heart to screen drugs
A Coventry University scientist has developed a pioneering new way – using samples of beating heart tissue – to test the effect of drugs on the heart without using human or animal trials.
View ArticleDeveloping 'tissue chip' to screen neurological toxins
A multidisciplinary team at the University of Wisconsin-Madison and the Morgridge Institute for Research is creating a faster, more affordable way to screen for neural toxins, helping flag chemicals...
View ArticleTracking subtle brain mutations, systematically: Tool can trace and spatially...
DNA sequences were once thought to be identical from cell to cell, but it's increasingly understood that mutations can arise during brain development that affect only certain groups of brain cells. A...
View ArticleBioelectricity plays key role in brain development and repair
Research reported today by Tufts University biologists shows for the first time that bioelectrical signals among cells control and instruct embryonic brain development and manipulating these signals...
View ArticleScientists coax stem cells to form 3-D mini lungs
Scientists have coaxed stem cells to grow the first three-dimensional mini lungs.
View ArticleBreast cancer research uncovers the fountain of youth
The Fountain of Youth has been discovered and it's not in Florida as Ponce de Leon claimed. Instead, it was found in the mammary glands of genetically modified mice.
View ArticleAge-related inflammatory processes facilitate development of COPD
At present, there is a lack of effective treatments that target the causes of chronic obstructive pulmonary disease (COPD). Scientists of the Comprehensive Pneumology Center (CPC) at Helmholtz Zentrum...
View ArticleResearchers create model of early human heart development from stem cells
Researchers at the University of California, Berkeley, in collaboration with scientists at the Gladstone Institutes, have developed a template for growing beating cardiac tissue from stem cells,...
View ArticleClinical validation for LOXO-101 against TRK fusion cancer
The University of Colorado Cancer Center and Loxo Oncology, Inc., a biopharmaceutical company focused on the discovery, development and commercialization of targeted cancer therapies, today announced...
View ArticleScientists say fetal tissue essential for medical research
The furor on Capitol Hill over Planned Parenthood has stoked a debate about the use of tissue from aborted fetuses in medical research, but U.S. scientists have been using such cells for decades to...
View ArticleStem cell-derived kidneys connect to blood vessels when transplanted into mice
Various research groups are collecting different types of cells and turning them into induced pluripotent stem (iPS) cells that can then generate diverse types of cells and tissues in the body. Now...
View ArticleSaturated fatty acids linked to breast cancer in postmenopausal women
Fatty acids in the breast may be useful indicators of cancer in postmenopausal women, according to a new study published online in the journal Radiology. The results may help researchers determine the...
View ArticleResearchers identify breast microbiome/bacterial differences between healthy...
A team of Mayo Clinic researchers has identified evidence of bacteria in sterilely-obtained breast tissue and found differences between women with and without breast cancer. The findings are published...
View ArticleElimination of senescent cells improves lung function in mice
Most cells can divide only a limited number of times and eventually undergo permanent cell cycle arrest, a state known as cellular senescence. Cellular senescence is mediated by activation of specific...
View ArticleMicrocephaly discoveries made in non-Zika cases help explain abnormal brain...
Long before Zika virus made it a household word, the birth defect called microcephaly puzzled scientists and doctors—even as it changed the lives of the babies born with it during the pre-Zika era.
View ArticleStudy reaffirms the belief that malignant cell behavior is influenced by the...
(Medical Xpress)—A team of researchers affiliated with several institutions in the U.S. has conducted a study of cancer in mice and found evidence that reaffirms results from prior research suggesting...
View ArticleComposite biomaterial scaffolds enable patterning of tissue architecture and...
Three-dimensional culture of stem cells in biomaterials has recently enabled the formation of complex cellular structures and miniature organoid tissues, including tissues resembling brain, spinal...
View ArticleResearchers propose mechanism for spread of metastatic breast cancer to bone
New research explains how metastatic breast cancer cells might use bone marrow-derived mesenchymal stem cells (MSCs) to help them spread to bone tissue. A study using a 3D scaffold model has shown that...
View ArticleBuilding a better brain
When you build models, whether ships or cars, you want them to be as much like the real deal as possible. This quality is even more crucial for building model organs, because disease treatments...
View ArticleStudy shows how an opportunistic microbe kills cancer cells
New study results show for the first time how dying cells ensure that they will be replaced, and suggests an ingenious, related new approach to shrinking cancerous tumors. A research team from Rush...
View ArticleNew breast cell types discovered by multidisciplinary research team
A joint effort by breast cancer researchers and bioinformaticians has provided new insights into the molecular changes that drive breast development.
View ArticleForces from fluid in the developing lung play an essential role in organ...
It is a marvel of nature: during gestation, multiple tissue types cooperate in building the elegantly functional structures of organs, from the brain's folds to the heart's multiple chambers. A recent...
View ArticleClinical trial tests feasibility of targeting particular classes of tumor...
A large team of researchers from the U.S., Spain and Australia has found that the efficacy of drugs for treating cancer aimed at targeting particular classes of mutations depends on the type of tumor...
View ArticleLab-grown eggs could pave way towards new fertility treatments
Human eggs have been fully grown in a laboratory, in a move that could lead to improved fertility treatments.
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